BrainsCAN: Brain health for life

BrainsCAN：终生大脑健康

• 批准号: 10009000024-2017
• 负责人: Daley, Mark
• 金额: $ 189.76万
• 依托单位: University of Western Ontario
• 依托单位国家: 加拿大
• 项目类别: Canada First Research Excellence Fund
• 财政年份: 2017
• 资助国家: 加拿大
• 起止时间: 2017-01-01 至 2018-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=643275
• 关键词: BrainsCAN; Brain; health; life

The neural mechanisms that give rise to human thought are harder to probe than the farthest reaches of the universe. Yet, understanding how brain networks support our actions, thoughts and emotions, and how these become disrupted in disorders that affect humans across their lifespan, are fundamentally important questions. Answering these questions will profoundly impact how we understand ourselves, each other, and the societies in which we live. Researchers at Western University, along with their national and international academic and commercial partners, will deliver evidence-based assessments and interventions for the diagnosis and treatment of disorders of the brain. These approaches will be informed by answers to fundamental aspects of how we learn, think, move and communicate. Understanding higher brain functions is central to diagnosing, classifying and treating psychiatric and neurological diseases; improving childhood learning and communication; optimizing neurosurgical interventions; and developing intelligent devices and algorithms. Technological innovation is a key to understanding higher brain functions, and will also further the application of that understanding. In such innovation, there lies considerable potential to stimulate a knowledge-based Canadian economy and benefit society as a whole. Building on decades of success in competitive federal grant programs, and fuelled by substantial strategic institutional support, Western University has become home to a large cluster of world-renowned researchers who study brain function, utilizing: state-of-the-art tools for investigating human cognitive performance, unique animal models, and leading facilities that can image across species. Already ranked amongst the best in the world in cognitive neurosciences and neuroimaging, Western University excels in the breadth of cognitive, computational, clinical, technological and translational approaches required for understanding and intervening in brain function. In partnership with the Canada First Research Excellence Fund, the BrainsCAN initiative will accelerate the university’s ability to deliver effective solutions to the grand challenge of maintaining brain function across the lifespan.

产生人类思想的神经机制比宇宙最遥远的地方更难探索。然而，了解大脑网络如何支持我们的行为、思想和情感，以及这些网络如何在影响人类一生的疾病中受到干扰，是至关重要的问题。回答这些问题将深刻影响我们如何理解自己、彼此以及我们所生活的社会。 西方大学的研究人员及其国内和国际学术和商业合作伙伴将为大脑疾病的诊断和治疗提供循证评估和干预措施。这些方法将基于我们如何学习、思考、行动和交流的基本方面的答案。 了解高级大脑功能对于精神和神经疾病的诊断、分类和治疗至关重要；改善儿童学习和交流；优化神经外科干预措施；开发智能设备和算法。技术创新是理解大脑高级功能的关键，也将进一步推动这种理解的应用。这种创新具有巨大的潜力来刺激以知识为基础的加拿大经济并造福整个社会。 凭借几十年来在竞争性联邦拨款项目中取得的成功，并在大量战略机构支持的推动下，西部大学已成为一大批世界知名研究人员的家园，他们研究大脑功能，利用：用于研究人类认知表现的最先进的工具、独特的动物模型以及可跨物种成像的领先设施。 西安大略大学在认知神经科学和神经影像学领域已跻身世界前茅，在理解和干预大脑功能所需的认知、计算、临床、技术和转化方法方面表现出色。 BrainsCAN 计划与加拿大第一卓越研究基金合作，将加速该大学提供有效解决方案的能力，以应对在整个生命周期中维持大脑功能的重大挑战。