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ConCRISPR: Conjugative delivery of a hybrid CRISPR/Tev nuclease system for specific microbiota modulation in the mammalian gut

ConCRISPR: Conjugative delivery of a hybrid CRISPR/Tev nuclease system for specific microbiota modulation in the mammalian gut
ConCRISPR:混合 CRISPR/Tev 核酸酶系统的接合递送,用于哺乳动物肠道中特定微生物群的调节
批准号:
380426
负责人:
Edgell David R
金额:
$64.93万
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2018
资助国家:
加拿大
项目状态:
已结题
起止时间:
2018-03-01 至 2023-03-01

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Edgell David R的其他基金

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中文摘要
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英文摘要
The human microbiota, composing the bacteria that live on or in us, is crucial for human development, health and disease. The discovery of antibiotics transformed our ability to control the human microbiota and resulted in a dramatic increase in survival
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Precision microbiome editing with CRISPR nucleases
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    489601
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    2023
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Enhancing CRISPR genome-editing outcomes with the TevCas9 dual nuclease
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  • 财政年份:
    2016
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Use of Tev-Cas9 dual nucleases to bias genome editing outcomes towards homology directed repair
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    351834
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Influences of homing endonucleases on gene structure and function
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    179626
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  • 负责人:
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