Molecular and Functional Characterization of Childhood Ependymoma

儿童室管膜瘤的分子和功能特征

• 批准号: 381502
• 负责人: Ramaswamy Vijay
• 金额: $ 66.6万
• 依托单位: Hospital for Sick Children (Toronto)
• 依托单位国家: 加拿大
• 项目类别: Operating Grants
• 财政年份: 2018
• 资助国家: 加拿大
• 起止时间: 2018-03-01 至 2023-03-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=381502&lang=en
• 关键词: Cancer; Ependymoma; Epigenetics; Genomics; Pediatric

Ependymoma is a major cause of childhood cancer related morbidity and mortality. Current therapies are limited to aggressive surgeries and external beam irradiation, which is effective in only 50% of cases, while resulting in significant lifelong neurocog

室管膜瘤是儿童癌症相关发病率和死亡率的主要原因。目前的治疗方法仅限于积极的手术和外部光束照射，这在只有50%的病例中有效，但会导致显著的终身神经病变。