Unveiling the role of alpha-synuclein clustering and Lewy body formation in Parkinson's disease pathogenesis using an optogenetic-mediated protein aggregation system
Unveiling the role of alpha-synuclein clustering and Lewy body formation in Parkinson's disease pathogenesis using an optogenetic-mediated protein aggregation system
批准号:
389427
负责人:
Oueslati Abid
金额:
$52.94万
依托单位:
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2018
资助国家:
加拿大
项目状态:
已结题
起止时间:
2018-09-01 至 2023-09-01
中文摘要
一个多世纪前,神经学家弗里德里希·路易首次描述了帕金森氏病(PD)患者的大脑中存在异常的蛋白质包涵体,称为路易小体(Lbs)。这些包裹体都是很棒的
英文摘要
More than a century ago, the neurologist Friedrich Lewy described for the first time, in the brain of patients suffering from Parkinson's disease (PD), the presence of abnormal protein inclusions, called Lewy bodies (LBs). These inclusions have been sugge
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
海外基金