Quantitative analysis of calcium arrhythmogenicity in the Purkinje fibers of ischemic heart: a search for the molecular origins of Sudden Cardiac Death.

缺血性心脏浦肯野纤维中钙致心律失常的定量分析：寻找心脏性猝死的分子起源。

• 批准号: 388618
• 负责人: Stuyvers Bruno
• 金额: $ 42.91万
• 依托单位: Memorial University of Newfoundland
• 依托单位国家: 加拿大
• 项目类别: Operating Grants
• 财政年份: 2018
• 资助国家: 加拿大
• 起止时间: 2018-09-01 至 2022-09-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=388618&lang=en
• 关键词: Abnormal Calcium; Calcium Electrogenicity; Cardiac Conduction; Cardiac Purkinje Cells; Delayed Afterdepolarization; Ischemia; Myocardial Infarction; Sudden Cardiac Death; Ventricular Tachycardia; Ventricullar Fibrillation

Heart diseases remain the first cause of mortality in the world. In Canada, it affects 1.4 million people, taking more than 50,000 lives per year in the country. Half of this mortality is due to heart failure, a progressive deterioration of cardiac contra

心脏病仍然是世界上死亡的第一大原因。在加拿大，它影响了140万人，每年夺走该国5万多人的生命。其中一半的死亡是由于心力衰竭，即心脏收缩的进行性恶化。