Sex-dependent Differences in pathophysiological mechanisms, presentation, outcome, and treatment of aortic valve stenosis

主动脉瓣狭窄的病理生理机制、表现、结果和治疗的性别依赖性差异

• 批准号: 393244
• 负责人: Clavel Marie-Annick
• 金额: $ 25.13万
• 依托单位: Institut universitaire de cardiologie et de pneumologie de Qubec - U Laval
• 依托单位国家: 加拿大
• 项目类别: Salary Programs
• 财政年份: 2018
• 资助国家: 加拿大
• 起止时间: 2018-09-01 至 2021-09-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=393244&lang=en
• 关键词: Aortic Stenosis; Calcification; Epidemiology; Fibrosis; Mouse Model; Sex-Differences

Aortic valve stenosis is the narrowing of the valve between the left ventricle of the heart and the aorta. This narrowing is an obstacle to the ejection of the blood from the heart to the rest of the body. When the disease is severe, the work of the heart

主动脉瓣狭窄是指心脏左室和主动脉之间的瓣膜变窄。这种狭窄是血液从心脏射入身体其他部位的障碍。当疾病很严重时，心脏的工作