Overcoming barriers to antibiotic production in Streptomyces bacteria

克服链霉菌细菌生产抗生素的障碍

• 批准号: 390484
• 负责人: Elliot Marie A
• 金额: $ 66.6万
• 依托单位: McMaster University
• 依托单位国家: 加拿大
• 项目类别: Operating Grants
• 财政年份: 2018
• 资助国家: 加拿大
• 起止时间: 2018-09-01 至 2023-09-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=390484&lang=en
• 关键词: Antibiotics; Cryptic Antibiotic Clusters; Gene Regulation; Heterologous Expression; Microbial Genetics; Molecular Biology; Morphological Development; Nucleoid-Associated Proteins; Spatial Segregation; Streptomyces

Antibiotic resistance is fast becoming a global health crisis: disease-causing bacteria are no longer killed by existing antibiotics, and we urgently need new drugs to help treat infectious disease. Most antibiotics are made by bacteria called 'Streptomyc

抗生素耐药性正在迅速成为全球健康危机：现有的抗生素不再能杀死致病细菌，我们迫切需要新的药物来帮助治疗传染病。大多数抗生素都是由一种叫做“链霉菌”的细菌制造的