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Inhibiting the MNK1/2-eIF4E axis, to favor anti-tumor immunity in melanoma.

Inhibiting the MNK1/2-eIF4E axis, to favor anti-tumor immunity in melanoma.
抑制 MNK1/2-eIF4E 轴,有利于黑色素瘤的抗肿瘤免疫。
批准号:
389880
负责人:
Del Rincon Sonia V
金额:
$55.45万
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2018
资助国家:
加拿大
项目状态:
已结题
起止时间:
2018-09-01 至 2023-09-01

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英文摘要
Our immune systems can recognize and eliminate cancer cells. However, sometimes cancer cells develop modes of hiding from immune system recognition. We predict that a specific protein synthesis pathway (known as the MNK1/2-eIF4e axis) is responsible, at l
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