Identifying clinically-relevant circulating protein biomarkers for osteoporosis

鉴定骨质疏松症的临床相关循环蛋白生物标志物

• 批准号: 397271
• 负责人: Zhou Sirui
• 金额: $ 9.83万
• 依托单位: Lady Davis Institute for Medical Research (Mtl)
• 依托单位国家: 加拿大
• 项目类别: Fellowship Programs
• 财政年份: 2018
• 资助国家: 加拿大
• 起止时间: 2018-11-01 至 2021-11-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=397271&lang=en
• 关键词: Bone Mineral Density; Circulating Protein Biomarkers; Fracture; Genome-Wide Association Study; Machine Learning Prediction; Mendelian Randomization

Osteoporosis is an aging-related skeletal disease and a major cause of morbidity and mortality. While therapies currently exist to prevent fractures, current risk stratification algorithms fail to identify the majority of people who fracture. Thus, a majo

骨质疏松症是一种与衰老相关的骨骼疾病，是发病率和死亡率的主要原因。虽然目前存在预防骨折的治疗方法，但目前的风险分层算法无法识别大多数骨折患者。因此，一场重大的