Cell populations regulating opioid-induced respiratory depression in sleep-wake states

在睡眠-觉醒状态下调节阿片类药物引起的呼吸抑制的细胞群

• 批准号: 399680
• 负责人: Rousseau Jean-Philippe
• 金额: $ 8.2万
• 依托单位: Unity Health Toronto
• 依托单位国家: 加拿大
• 项目类别: Fellowship Programs
• 财政年份: 2018
• 资助国家: 加拿大
• 起止时间: 2018-11-01 至 2021-11-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=399680&lang=en
• 关键词: Analgesia; Brainstem Cell Populations; Central Nervous System; Control Of Breathing; Electrocorticals Recordings; Opioids; Optogenetics; Prebötzinger Complex; Respiratory Depression; Whole Body Respiratory Recordings

Opioids are used extensively for their analgesic properties but they have a variety of unwanted side effects, including tolerance, dependence, and most signicantly, respiratory depression. According to the Public Health Agency of Canada, there were more t

阿片类药物因其镇痛特性而被广泛使用，但它们有多种不良副作用，包括耐受性、依赖性，最重要的是呼吸抑制。据加拿大公共卫生局称，有更多