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Investigating the contributions of mitochondrial dysfunction and impaired neuromuscular junction integrity to the aging-related loss of muscle mass and function in humans

Investigating the contributions of mitochondrial dysfunction and impaired neuromuscular junction integrity to the aging-related loss of muscle mass and function in humans
研究线粒体功能障碍和神经肌肉接头完整性受损对人类衰老相关肌肉质量和功能丧失的影响
批准号:
398889
负责人:
Gouspillou Gilles
金额:
$32.78万
依托单位:
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2018
资助国家:
加拿大
项目状态:
已结题
起止时间:
2018-11-01 至 2021-11-01

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中文摘要
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英文摘要
One of the most significant changes associated with normal aging is a progressive loss of muscle mass and strength, a biological process called sarcopenia. Sarcopenia can lead to mobility impairment, falls, and physical frailty in the elderly, dramaticall
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Evidence for PGC-1a mediated angiogenesis in human muscle: Insights from energetic deficiency in mitochondrial myopathy
  • 批准号:
    263331
  • 项目类别:
  • 资助金额:
    $0.07万
  • 财政年份:
    2012
  • 负责人:
    Gouspillou Gilles
  • 依托单位:
海外基金