CRISPR-Cas9 targeting of secretory pathway furin in human cells: Insights into the biological roles of furin in the flaviviral lifecycle.

CRISPR-Cas9 靶向人类细胞中的分泌途径弗林蛋白酶：深入了解弗林蛋白酶在黄病毒生命周期中的生物学作用。

• 批准号: 406422
• 负责人: Chan Carly C
• 金额: $ 1.27万
• 依托单位: University of Calgary
• 依托单位国家: 加拿大
• 项目类别: Studentship Programs
• 财政年份: 2018
• 资助国家: 加拿大
• 起止时间: 2018-12-01 至 2019-12-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=406422&lang=en
• 关键词: 2d Cell Culture And 3d Brain Organoid Models; Cell Toxicity And Antiviral Effects; Crispr-Cas9 Gene Editing; Flaviviruses (Dengue; Host Factor Knockouts; Host Factors In Viral Life Cycles; Host Secretory Pathway Furin; Human Pluripotent Stem Cell-Derived

CRISPR-Cas9 targeting of secretory pathway furin in human cells: Insights into the biological roles of furin in the flaviviral lifecycle. There is currently a lack of therapeutic options to treat neurotropic viral diseases caused by flaviviruses like De

CRISPR-Cas9靶向人细胞分泌通路furin: furin在黄病毒生命周期中的生物学作用目前缺乏治疗由黄病毒引起的嗜神经病毒疾病的方法