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Computational modelling of interplay between histone tail modifications and its effects on chromatin dynamics in human development and cancer

Computational modelling of interplay between histone tail modifications and its effects on chromatin dynamics in human development and cancer
组蛋白尾部修饰之间相互作用及其对人类发育和癌症染色质动力学影响的计算模型
批准号：
406343
负责人：
Hu Bo
金额：
$1.27万
依托单位：
McGill University
依托单位国家：
加拿大
项目类别：
Studentship Programs
财政年份：
2018
资助国家：
加拿大
项目状态：
已结题
起止时间：
2018-12-01 至 2019-12-01
来源：
https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=406343&lang=en
关键词：
Bioinformatics Carcinogenesis Chromatin Remodelling Computational Modelling Dna Methylation Epigenetics Gene Regulation Histone Modifications Oncohistones

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中文摘要
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英文摘要
The causes of cancer have long been an important area of research, and recent studies have indicated an under-appreciation of “epigenetic” changes' contribution to the development of cancer, which concern the chemical modifications to DNA or to the protei
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Resolving the cis-regulatory role of the histone post-translational modification H3K36me2 in driving tumorigenesis
  • 批准号：
    439495
  • 项目类别：
    Studentship Programs
  • 资助金额：
    $7.65万
  • 财政年份：
    2020
  • 负责人：
    Hu Bo
  • 依托单位：
    McGill University
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