CRISPR/Cas9 Mediated Knockout of PGC1a to Propose the Zebrafish as a Biomedical Model for Treating Metabolic Diseases

CRISPR/Cas9 介导的 PGC1a 敲除提议斑马鱼作为治疗代谢性疾病的生物医学模型

• 批准号: 415524
• 负责人: Kurchaba Nicholas
• 金额: $ 1.27万
• 依托单位: Brandon University (Manitoba)
• 依托单位国家: 加拿大
• 项目类别: Studentship Programs
• 财政年份: 2018
• 资助国家: 加拿大
• 起止时间: 2018-12-01 至 2019-12-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=415524&lang=en
• 关键词: Biomedical Applications; Biomedical Model; Environmental Influences; Gene Knockdown; Gene Role; Health; Metabolism; Multiple Diseases; Nuerological; Pgc1a

All biological life is dependent on energy acquisition and expenditure in order to survive, reproduce and thrive. Most of our energy is derived from the mitochondria, an organelle responsible for converting nutrients into energy with the use of oxygen a

所有生物都依赖于能量的获取和消耗来生存， 繁衍生息我们的大部分能量来自线粒体，一种细胞器 负责利用氧气将营养物质转化为能量，