Investigation of Shank-interacting protein-like 1 (SIPL1)-mediated PTEN inactivation during breast tumorigenesis
Investigation of Shank-interacting protein-like 1 (SIPL1)-mediated PTEN inactivation during breast tumorigenesis
批准号:
205080
负责人:
Tang Damu
金额:
$7.29万
依托单位:
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2009
资助国家:
加拿大
项目状态:
已结题
起止时间:
2009-09-01 至 2010-09-01
中文摘要
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英文摘要
PTEN is a critical tumour suppressor that prevents breast cancer formation. Clinical observations have shown that a loss of PTEN occurs in high percentages (up to 50%) of HER2-positive and basal-like breast cancers, the two subgroups that are associated w
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