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Does the absence of dystrophin during somitogenesis dysregulate myogenic progenitor cell divisions and differentiation in the mdx mouse

Does the absence of dystrophin during somitogenesis dysregulate myogenic progenitor cell divisions and differentiation in the mdx mouse
mdx 小鼠体节发生过程中肌营养不良蛋白的缺失是否会导致肌原祖细胞分裂和分化失调
批准号:
416189
负责人:
Esper Marie E
金额:
$1.27万
依托单位:
依托单位国家:
加拿大
项目类别:
Studentship Programs
财政年份:
2018
资助国家:
加拿大
项目状态:
已结题
起止时间:
2018-12-01 至 2019-12-01

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英文摘要
Duchenne Muscular Dystrophy (DMD) is a fatal muscle degenerative disease that afflicts 1 in 3500 male children. DMD is caused by a loss-in-function mutation to the protein Dystrophin which normally maintains muscle fibre structure and regulates the divisi
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