Fast characterization of multiple prion strains in cultured murine neuronal organotypic slices

培养的鼠神经元器官切片中多种朊病毒株的快速表征

• 批准号: 406376
• 负责人: Slota Jessy A
• 金额: $ 1.27万
• 依托单位: University of Manitoba
• 依托单位国家: 加拿大
• 项目类别: Studentship Programs
• 财政年份: 2018
• 资助国家: 加拿大
• 起止时间: 2018-12-01 至 2019-12-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=406376&lang=en
• 关键词: Disease Transmission; Ex Vivo Models; Genetic Engineering; Infection; Neurodegeneration; Neuronal Death; Pathogenesis; Prions; Strain Typing

Prion diseases are a group of fatal diseases that affect both humans and animals. They result in death of brain cells and a decline in the mental capacity of affected individuals. The disease causing agent is called a prion, which is a misfolded form of a

朊病毒病是一组影响人类和动物的致命疾病。它们导致脑细胞死亡和受影响个体的智力下降。致病因子被称为朊病毒，它是一种错误折叠的