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Target validation of ACLY as a novel anti-cancer drug target for hepatocellular carcinoma

Target validation of ACLY as a novel anti-cancer drug target for hepatocellular carcinoma
ACLY作为肝细胞癌新型抗癌药物靶点的靶点验证
批准号:
406582
负责人:
Wu Jianhan
金额:
$1.27万
依托单位:
依托单位国家:
加拿大
项目类别:
Studentship Programs
财政年份:
2018
资助国家:
加拿大
项目状态:
已结题
起止时间:
2018-12-01 至 2019-12-01

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中文摘要
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英文摘要
ATP citrate lyase (ACLY) performs an essential role in de novo lipogenesis by catalyzing the synthesis of cytosolic acetyl-CoA. De novo lipogenesis is upregulated in cancer in order to compensate for the metabolic demands of rapid cell proliferation. This
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Elucidating the relationship between molecular biomarkers of aging and metabolic multimorbidity
  • 批准号:
    457493
  • 项目类别:
    Studentship Programs
  • 资助金额:
    $10.93万
  • 财政年份:
    2021
  • 负责人:
    Wu Jianhan
  • 依托单位:
海外基金