Identification of a novel compound that reduces mortality from severe influenza and elucidation of its molecular mechanisms

鉴定一种可降低严重流感死亡率的新型化合物并阐明其分子机制

• 批准号: 406543
• 负责人: Latreille Elyse
• 金额: $ 1.27万
• 依托单位: University of Toronto
• 依托单位国家: 加拿大
• 项目类别: Studentship Programs
• 财政年份: 2018
• 资助国家: 加拿大
• 起止时间: 2018-12-01 至 2019-12-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=406543&lang=en
• 关键词: Endothelial Activation; Influenza; Innate Immunity; Intercellular Adhesion Molecule 1; Lung Injury

The influenza virus causes hundreds of thousands of deaths annually worldwide. There is a constant threat of a novel strain developing, leading to an influenza pandemic. While antivirals exist for the treatment of infections, the virus changes quickly and

流感病毒每年在全世界造成数十万人死亡。一种新的毒株不断出现，从而导致流感大流行。虽然存在治疗感染的抗病毒药物，但病毒变化很快，而且