The Role of Microvascular Function in Bed Rest Induced Insulin Resistance and the Countermeasure Potential of High Intensity Interval Training

微血管功能在卧床引起的胰岛素抵抗中的作用以及高强度间歇训练的对策潜力

• 批准号: 406367
• 负责人: Biddlecombe Jesse R
• 金额: $ 1.27万
• 依托单位: Thompson Rivers University (Kamloops, BC)
• 依托单位国家: 加拿大
• 项目类别: Studentship Programs
• 财政年份: 2018
• 资助国家: 加拿大
• 起止时间: 2018-12-01 至 2019-12-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=406367&lang=en
• 关键词: Bed Rest; Endothelium Dysfunction; Extracellular Vesicles; High Intensity Interval Training; Hyperinsulinemia; Insulin Resistance; Macrovascular Dysfunction; Microvascular Dysfunction; Microvesicles; Transcytosis

Physical inactivity and muscle disuse, particularly bed rest, induces insulin resistance from which recovery is prolonged and often incomplete in persons of middle age. As such, along with change in glucose concentrations, the impact of vascular changes o

缺乏体力活动和肌肉废用，特别是卧床休息，会导致胰岛素抵抗，中年人的恢复时间很长，而且往往不完全。因此，沿着葡萄糖浓度的变化，