Functional dissection of the role of the Anaphase Promoting Complex in cellular longevity

后期促进复合物在细胞寿命中的作用的功能剖析

• 批准号: 403704
• 负责人: Harkness Troy A
• 金额: $ 63.53万
• 依托单位: University of Saskatchewan
• 依托单位国家: 加拿大
• 项目类别: Operating Grants
• 财政年份: 2019
• 资助国家: 加拿大
• 起止时间: 2019-03-01 至 2024-03-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=403704&lang=en
• 关键词: Anaphase Promoting Complex (Apc); Apc Binding And Activating Peptides; Genetics, Biochemistry And Microscopy; Human Progeria Primary Fibroblasts; Longevity; Nutrient Sensing; Protein Stability; Stress Sensing; Yeast; Yeast Progeria Model

Humans are living longer than ever before, but it is often with age-related illnesses. Almost 100 years of research indicates that aging and age-related disease can be delayed, for example, through caloric restriction. While a great deal has been learned

人类的寿命比以往任何时候都长，但往往伴随着与年龄有关的疾病。近100年的研究表明，衰老和与年龄有关的疾病可以延缓，例如，通过限制热量摄入。虽然我们学到了很多东西