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What are the implications of Anti-HIV drugs interaction with Transporters proteins in: Anatomical Viral reservoirs persistence, cytotoxicity and co-infection?

What are the implications of Anti-HIV drugs interaction with Transporters proteins in: Anatomical Viral reservoirs persistence, cytotoxicity and co-infection?
抗 HIV 药物与转运蛋白相互作用对以下方面有何影响：解剖学病毒储存库持久性、细胞毒性和合并感染？
批准号：
199385
负责人：
Haimeur Anass
金额：
$7.29万
依托单位：
Centre hospitalier de l'Universit Laval (Qubec)
依托单位国家：
加拿大
项目类别：
Operating Grants
财政年份：
2009
资助国家：
加拿大
项目状态：
已结题
起止时间：
2009-09-01 至 2010-09-01
来源：
https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=199385&lang=en
关键词：
Abc Transporters Anti-Hiv Drug And Protein Interactions Anti-Hiv Drug Clearance Hiv/Aids Photo-Affinity Labeling Protein Engineering

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英文摘要
Highly Active Anti-Retroviral Therapy (HAART) has achieved high-level suppression of viral load in HIV-1-infected patients. The idea behind the HAART is to bloc different steps in the viral cycle by using combination of different antiviral drug classes. U
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