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Mechanisms that impact the cell division axis and phenotype for BRCA1-mutant mammary epithelial cells.

Mechanisms that impact the cell division axis and phenotype for BRCA1-mutant mammary epithelial cells.
影响 BRCA1 突变乳腺上皮细胞细胞分裂轴和表型的机制。
批准号：
408934
负责人：
Maxwell Christopher A
金额：
$61.02万
依托单位：
BC Children's Hospital Research Institute
依托单位国家：
加拿大
项目类别：
Operating Grants
财政年份：
2019
资助国家：
加拿大
项目状态：
已结题
起止时间：
2019-09-01 至 2024-09-01
来源：
https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=408934&lang=en
关键词：
Brca1 Cell Fate/ Differentiation Cell Proliferation Inherited Disease

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中文摘要
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英文摘要
Young women who develop breast cancer often have inherited a change to a gene called BRCA1. We are studying how these inherited changes affect the growth of mammary cells. We have identified that harmful or pathogenic changes in BRCA1, those that associat
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