Carbapenemase inhibitors for use as adjuvants in treating carbapenem-resistant bacterial infections

碳青霉烯酶抑制剂用作治疗碳青霉烯类耐药细菌感染的佐剂

• 批准号: 410078
• 负责人: Dmitrienko Gary I
• 金额: $ 49.04万
• 依托单位: University of Waterloo (Ontario)
• 依托单位国家: 加拿大
• 项目类别: Operating Grants
• 财政年份: 2019
• 资助国家: 加拿大
• 起止时间: 2019-09-01 至 2022-09-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=410078&lang=en
• 关键词: Antibiotics; Enzyme Inhibitors; Enzymology; Medicinal Chemistry; Microbiology; Molecular Modelling; Organic Synthesis

Increasingly, bacterial infections, particularly those acquired in hospitals, are being caused by bacteria that are resistant to current antibiotics. In order to ensure that a last line of defense is available in such cases, antibiotics, such as the carba

越来越多的细菌感染，特别是在医院获得的细菌感染，是由对当前抗生素具有耐药性的细菌引起的。为了确保在这种情况下有最后一道防线，抗生素，如碳水化合物