Role of PKM2/oxidative DNA damage axis in the pathogenesis of Right Ventricular Failure associated with Pulmonary Arterial Hypertension
Role of PKM2/oxidative DNA damage axis in the pathogenesis of Right Ventricular Failure associated with Pulmonary Arterial Hypertension
批准号:
411816
负责人:
SHIMAUCHI Tsukasa
金额:
$0.07万
依托单位国家:
加拿大
项目类别:
财政年份:
2019
资助国家:
加拿大
项目状态:
已结题
起止时间:
2019-09-01 至 2020-09-01
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中文摘要
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英文摘要
Background: Right ventricular failure (RVF) is an independent prognostic factor for pulmonary arterial hypertension (PAH) patients. Recent studies have demonstrated that a metabolic shift toward increased glycolysis over glucose oxidation (Warburg effect)
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