Targeting the NO-sGC axis for the treatment of organ hypoperfusion in sepsis and septic shock

靶向 NO-sGC 轴治疗脓毒症和脓毒性休克器官灌注不足

• 批准号: 412216
• 负责人: Jahandideh Forough
• 金额: $ 0.07万
• 依托单位: University of Alberta
• 依托单位国家: 加拿大
• 财政年份: 2019
• 资助国家: 加拿大
• 起止时间: 2019-09-01 至 2020-09-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=412216&lang=en
• 关键词: Circulatory Collapse; Nitric Oxide Signaling; Organ Blood Flow; Sepsis; Vascular Function; Vasodilation

Background: Sepsis (blood poisoning) is a medical condition in which overwhelming infection in the body can no longer be contained by the body's natural defenses. This infection can start in almost any organ and can spread throughout the body. If untreate

背景： 败血症(血液中毒)是一种身体内压倒性的感染不再能被身体的自然防御系统控制的医学状况。这种感染可以从几乎任何器官开始，并可以传播到全身。如果不处理