Oxygen (O2) and carbon dioxide (CO2) sensors in airway chemoreceptors: Molecular characterization and physiological functions

气道化学感受器中的氧气 (O2) 和二氧化碳 (CO2) 传感器：分子特征和生理功能

• 批准号: 189921
• 负责人: Cutz Ernest
• 金额: $ 52.91万
• 依托单位: Hospital for Sick Children (Toronto)
• 依托单位国家: 加拿大
• 项目类别: Operating Grants
• 财政年份: 2009
• 资助国家: 加拿大
• 起止时间: 2009-09-01 至 2014-09-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=189921&lang=en
• 关键词: Bpd; Carbon Dioxide Sensing; Confocal Microscopy; Control Of Breathing; Electrophysiology; Immunohistochemistry; K/O Mice Models; Molecular; Neonatal Respiratory Adaptation; Nicotine Induced Neb Changes; Oxygen Sensing; Patch-Clamp Method; Sids; Tissue Cu

We study specialized groups of lung cells called neuroepithelial bodies or NEB, located within airways of human and animal lungs. NEB are postulated to function as oxygen and potentially carbon dioxide sensors in lung with greatest importance during neona

我们研究了位于人类气道内的被称为神经上皮小体或NEB的肺细胞的特殊群体， 动物的肺NEB被假定在肺中充当氧气和潜在的二氧化碳传感器， 新生儿期重要性