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A pilot study for brain delivery of recombinant glucocerebrosidase in people with Parkinson's disease using MR-guided focused ultrasound induced opening of the blood-brain barrier

A pilot study for brain delivery of recombinant glucocerebrosidase in people with Parkinson's disease using MR-guided focused ultrasound induced opening of the blood-brain barrier
使用 MR 引导聚焦超声诱导血脑屏障开放，对帕金森病患者脑部输送重组葡萄糖脑苷酶的初步研究
批准号：
412563
负责人：
Meng Ying
金额：
$8.01万
依托单位：
Sunnybrook Research Institute (Toronto, Ontario)
依托单位国家：
加拿大
项目类别：
Fellowship Programs
财政年份：
2019
资助国家：
加拿大
项目状态：
已结题
起止时间：
2019-10-01 至 2021-10-01
来源：
https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=412563&lang=en
关键词：
Blood-Brain Barrier Disease-Modifying Therapy Drug Delivery Enzyme Replacement Glucocerebrosidase Image-Guided Therapy Minimally-Invasive Procedure Mr-Guided Focused Ultrasound Parkinson'S Disease

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中文摘要
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英文摘要
Parkinson's disease (PD) is the second most prevalent neurodegenerative disorder, affecting 1-2 per 1000 people. There's a need for disease-modifying therapy in PD, but many potentially effective therapeutics are limited from the brain by the blood-brain
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会议论文
Towards focused ultrasound aided liquid biopsy of premalignant/malignant peripheral nerve sheath tumours
  • 批准号：
    491219
  • 项目类别：
    Fellowship Programs
  • 资助金额：
    $13.11万
  • 财政年份：
    2023
  • 负责人：
    Meng Ying
  • 依托单位：
    University Health Network (Toronto)
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