FGF2 Isoforms in Cardiac Hypertrophy

心脏肥大中的 FGF2 亚型

• 批准号: 189823
• 负责人: Kardami Elissavet
• 金额: $ 59.6万
• 依托单位: St. Boniface General Hospital Research Centre (Winnipeg)
• 依托单位国家: 加拿大
• 项目类别: Operating Grants
• 财政年份: 2009
• 资助国家: 加拿大
• 起止时间: 2009-09-01 至 2014-09-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=189823&lang=en
• 关键词: Cardiac Hypertrophy; Fibroblast-Myocyte Interaction; Fibrosis; Growth Factor Isoform; Signal Transduction; Transgenic Models

Many cardiovascular diseases are characterized by abnormal heart growth, which predicts poor cardiac outcome. Our previous studies have indicated that a protein, believed to be involved in promoting abnormal growth, FGF2, is more complex than generally kn

许多心血管疾病的特征是心脏发育异常，这预示着心脏预后不良。我们以前的研究表明，一种被认为与促进异常生长有关的蛋白质，FGF2，比通常所知的要复杂得多。