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Unraveling the molecular mechanisms underlying cerebral blood flow deficits in a mouse model of Alzheimer's disease

Unraveling the molecular mechanisms underlying cerebral blood flow deficits in a mouse model of Alzheimer's disease
揭示阿尔茨海默病小鼠模型脑血流缺陷的分子机制
批准号：
412293
负责人：
Trigiani Lianne J
金额：
$10.93万
依托单位：
Cornell University (New York)
依托单位国家：
加拿大
项目类别：
Fellowship Programs
财政年份：
2019
资助国家：
加拿大
项目状态：
已结题
起止时间：
2019-10-01 至 2022-10-01
来源：
https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=412293&lang=en
关键词：
Alzheimer'S Disease Capillary Stalls Cerebral Circulation Endothelial Cells Neuroinflammation Oxidative Stress Perivascular Macrophages Two Photon Imaging

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相关文献

中文摘要
翻译
脑内血流量减少已被确定为阿尔茨海默病发展的早期事件。最近发现，阿尔茨海默病小鼠大脑中最小的血管毛细血管被阻塞了
英文摘要
Reductions in blood flow within the brain has been identified as an early event in the development of Alzheimer's disease. It was recently discovered that the smallest blood vessels, capillaries, in the brain of Alzheimer's disease mice were being blocked
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Impact of pharmacological therapy and physical exercise on cognitive function in hypercholesterolemic TGF mice
  • 批准号：
    331602
  • 项目类别：
    Studentship Programs
  • 资助金额：
    $1.27万
  • 财政年份：
    2014
  • 负责人：
    Trigiani Lianne J
  • 依托单位：
    McGill University