Second mitochondrial activator of caspases (SMAC) Mimetics as novel HIV Latency Reversal Agents for HIV eradication
Second mitochondrial activator of caspases (SMAC) Mimetics as novel HIV Latency Reversal Agents for HIV eradication
批准号:
417536
负责人:
Jain Jaspreet
金额:
$9.83万
依托单位国家:
加拿大
项目类别:
Fellowship Programs
财政年份:
2019
资助国家:
加拿大
项目状态:
已结题
起止时间:
2019-10-01 至 2022-10-01
中文摘要
抗逆转录病毒疗法(ART)将艾滋病毒的复制抑制到无法检测的水平。然而,潜伏病毒库(VR)的持续存在,主要由CD4+ T细胞组成,在某种程度上,巨噬细胞允许抗逆转录病毒治疗后病毒血症的反弹
英文摘要
Antiretroviral therapy (ART) suppresses HIV replication to undetectable levels. However, the persistence of latent viral reservoirs (VR) consisting majorly of CD4+ T cells and to some extent, macrophages allows for a rebound of viremia upon ART treatment
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
海外基金