Second mitochondrial activator of caspases (SMAC) Mimetics as novel HIV Latency Reversal Agents for HIV eradication
Second mitochondrial activator of caspases (SMAC) Mimetics as novel HIV Latency Reversal Agents for HIV eradication
批准号:
417536
负责人:
Jain Jaspreet
金额:
$9.83万
依托单位国家:
加拿大
项目类别:
Fellowship Programs
财政年份:
2019
资助国家:
加拿大
项目状态:
已结题
起止时间:
2019-10-01 至 2022-10-01
中文摘要
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英文摘要
Antiretroviral therapy (ART) suppresses HIV replication to undetectable levels. However, the persistence of latent viral reservoirs (VR) consisting majorly of CD4+ T cells and to some extent, macrophages allows for a rebound of viremia upon ART treatment
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