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Deciphering the Implementability of Epigenetic Reprogramming in Hematopoietic Stem Cells as a Novel Vaccination Strategy against Human Tuberculosis

Deciphering the Implementability of Epigenetic Reprogramming in Hematopoietic Stem Cells as a Novel Vaccination Strategy against Human Tuberculosis
破译造血干细胞表观遗传重编程作为人类结核病新型疫苗接种策略的可行性
批准号：
413227
负责人：
Kaufmann Eva
金额：
$9.83万
依托单位：
Research Institute of the McGill University Health Centre
依托单位国家：
加拿大
项目类别：
Fellowship Programs
财政年份：
2019
资助国家：
加拿大
项目状态：
已结题
起止时间：
2019-10-01 至 2022-10-01
来源：
https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=413227&lang=en
关键词：
Bcg Hematopoietic Stem Cells Humanized Mice Innate Immune System Mouse Models Mycobacterium Tuberculosis Trained Immunity Tuberculosis Vaccination

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Ever since the German scientist Robert Koch discovered Mycobacterium tuberculosis (Mtb) to be the infectious agent of tuberculosis in 1882, it has defied efforts by scientists to prevent or cure the disease. The presence of Mtb DNA in ancient Egyptian mum
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