Identification of Epigenomic Drivers and Predictors of Chordoma Development and Recurrence

脊索瘤占原发性脊柱和颅底肿瘤的20%，尽管进行了标准的手术治疗和术后放疗，但6-7年的中位生存率仍然很低。发生脉络膜复发的患者的手术效果较差。

Chordomas represent 20% of primary spine and skull base tumours and median survival remains poor at 6-7 years despite standard treatment of surgery and post-operative radiotherapy. Patients that develop a recurrence of their chordoma experience poorer sur