The role of exosomes in acute HIV-1 infection

外泌体在急性 HIV-1 感染中的作用

• 批准号: 192505
• 负责人: Gilbert Caroline
• 金额: $ 21.86万
• 依托单位: Universit Laval
• 依托单位国家: 加拿大
• 项目类别: Salary Programs
• 财政年份: 2009
• 资助国家: 加拿大
• 起止时间: 2009-09-01 至 2014-09-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=192505&lang=en
• 关键词: Acute Infection; Cd4 Immunodepletion; Dendritic Cells; Exosome Purification; Hiv-1; Signal Transduction

Immature dendritic cells (iDCs) which reside in these mucosal tissues capture internalize and serve as hidden reservoirs for the virions. This helps the virus escape immune surveillance during the DCs migration to the secondary lymphoid organs where the v

存在于这些粘膜组织中的未成熟树突状细胞（iDC）捕获内化并充当病毒体的隐藏储库。这有助于病毒在DCs迁移到次级淋巴器官的过程中逃避免疫监视，