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Interrogating the structural basis for protein interactions underlying mitochondrial calcium uniporter regulation in cardiomyocytes.

Interrogating the structural basis for protein interactions underlying mitochondrial calcium uniporter regulation in cardiomyocytes.
探究心肌细胞中线粒体钙单向转运蛋白调节的蛋白质相互作用的结构基础。
批准号：
420557
负责人：
Stathopulos Peter B
金额：
$49.04万
依托单位：
University of Western Ontario
依托单位国家：
加拿大
项目类别：
Operating Grants
财政年份：
2020
资助国家：
加拿大
项目状态：
未结题
起止时间：
2020-03-01 至 2025-03-01
来源：
https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=420557&lang=en
关键词：
Calcium Signaling Mcu Regulating Protein-1 Mitochondrial Calcium Uniporter Myocardial Infarction Protein Allostery Protein Structure Protein-Protein Interactions Solution Nmr

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Cancer and heart disease are responsible for almost 50 % of all deaths in Canada annually. In the past ten years these leading causes of mortality in both sexes have accounted for more than 1,250,000 Canadian deaths. Mitochondria are small compartments in
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