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Retention of PCSK9 in the endoplasmic reticulum acts as a co-chaperone to protect against liver injury/dysfunction

Retention of PCSK9 in the endoplasmic reticulum acts as a co-chaperone to protect against liver injury/dysfunction
PCSK9 在内质网中的保留充当共伴侣,以防止肝损伤/功能障碍
批准号:
418859
负责人:
Austin Richard C
金额:
$50.44万
依托单位:
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2020
资助国家:
加拿大
项目状态:
未结题
起止时间:
2020-03-01 至 2025-03-01

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中文摘要
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英文摘要
This study examines the role of PCSK9 retention on liver function/injury, including the development of hepatic steatosis. PCSK9 can regulate the development of cardiovascular disease (CVD). Individuals that do not produce enough PCSK9 from the liver are p
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海外基金