Physical Organic Chemistry of Materials

材料物理有机化学

• 批准号: RGPIN-2017-04637
• 负责人: Workentin, Mark
• 金额: $ 5.39万
• 依托单位: University of Western Ontario
• 依托单位国家: 加拿大
• 项目类别: Discovery Grants Program - Individual
• 财政年份: 2019
• 资助国家: 加拿大
• 起止时间: 2019-01-01 至 2020-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=691723
• 关键词: Physical; Organic; Chemistry; Materials

The @WorkentinChem Group's focus is to address fundamental physical organic aspects of interfacial organic reactions and to utilize the knowledge gained to design and synthesize new materials and to demonstrate potential applications. Reactions of molecules in solution are supported by a well-developed set of methods from physical organic chemistry, but the reactions of molecules at the interface of materials are not as well understood. We design and synthesize organic molecular systems that undergo specific thermal, photochemical, or electrochemical reactions to serve as probes of the interfacial material environment. Once understood these reactions provide new platforms for selective surface modifications to build new architectures. A cornerstone of our efforts focuses on understanding the mechanistic factors that are unique to interfacial reactions on metal nanoparticle surfaces and carbonaceous material. The importance and motivation behind these studies lies in the utility of these types of functional materials in the development of value added products in nano-medicine, bio-imaging, drug delivery, molecular and biomolecular electronics, sensors, catalysis etc. Our studies examine fundamental factors that control surface reactivity and molecular interactions in these unique nanomaterials. We are addressing these issues by examining photoinduced, redox activated and thermal reactivity in terms of chemical properties (structure-reactivity relationships, conformational and orientation mobility) and physical properties (structure, order-disorder phenomena, reaction conditions). A complete understanding of these factors is essential for the rational design and control of any modified surface for a particular application. ******To accomplish our goals, we recruit and train inquisitive and creative students at all levels (undergraduate B.Sc., M.Sc., Ph.D.). These personnel master a broad spectrum of core chemical competencies in organic synthetic methods and analysis, inorganic and organic materials chemistry, the specialized techniques for their characterization as well as advanced skills in electrochemistry, photochemistry and materials chemistry. Ultimately, these trained HQP become the creative minds driving the future of Canadian science and innovation. Trained HQP from the group are award winning and have had a 100% professional placement over the last 12+ years. ******The goals of this proposal are built on three foundational themes. We plan to: (1) Develop an interchangeable toolbox of interfacial reactions that can be used to functionalize materials rapidly, selectively, quantitatively and under mild conditions. 2) Develop strategies to make our technology transferable to a variety of materials. 3) Exploit these reactions towards innovative applications through effective collaboration within academia and industrial innovation contributors.

@WorkentinChem小组的重点是解决界面有机反应的基本物理有机方面，并利用所获得的知识来设计和合成新材料，并展示潜在的应用。分子在溶液中的反应得到了一套完善的物理有机化学方法的支持，但分子在材料界面上的反应却没有得到很好的理解。我们设计和合成有机分子系统，经过特定的热，光化学或电化学反应，作为界面材料环境的探针。一旦了解了这些反应，就为选择性表面修饰提供了新的平台，从而建立新的体系结构。我们努力的基石是理解金属纳米颗粒表面和碳质材料界面反应的独特机制因素。这些研究背后的重要性和动机在于这些类型的功能材料在纳米医学、生物成像、药物输送、分子和生物分子电子学、传感器、催化等附加值产品开发中的效用。我们的研究考察了控制这些独特纳米材料表面反应性和分子相互作用的基本因素。我们从化学性质（结构-反应关系、构象和取向迁移率）和物理性质（结构、有序-无序现象、反应条件）两方面考察光诱导、氧化还原活化和热反应性来解决这些问题。全面了解这些因素对于合理设计和控制任何特定应用的改性表面是必不可少的。******为了实现我们的目标，我们招募和培养各个层次的求知欲和创造力的学生（本科学士，硕士，博士）。这些人员掌握了广泛的核心化学能力，包括有机合成方法和分析，无机和有机材料化学，其表征的专业技术以及电化学，光化学和材料化学的高级技能。最终，这些训练有素的HQP成为推动加拿大科学和创新未来的创造性人才。在过去的12年里，该集团训练有素的HQP屡获殊荣，并有100%的专业安置。******本提案的目标建立在三个基本主题之上。我们计划：(1)开发一个可互换的界面反应工具箱，可用于在温和条件下快速，有选择性，定量地功能化材料。2)制定策略，使我们的技术可转移到各种材料。3)通过学术界和工业创新贡献者之间的有效合作，利用这些对创新应用的反应。