Manipulating cytokine pathways to increase T cell stemness during chronic antigen exposure
Manipulating cytokine pathways to increase T cell stemness during chronic antigen exposure
批准号:
434348
负责人:
Decaluwe Hlène
金额:
$65.2万
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2020
资助国家:
加拿大
项目状态:
未结题
起止时间:
2020-10-01 至 2025-10-01
中文摘要
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英文摘要
Chronic viral infections and cancer induce a state of immune unresponsiveness called "exhaustion". Multiple parameters have been shown by us and others to contribute to the exhaustion of T lymphocytes, including cytokines. These mediators may induce exhau
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会议论文
Persistence and potency of naturally-occuring and vaccine-induced memory T cells to SARS-Cov-2 variants
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批准号:450263
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项目类别:Operating Grants
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资助金额:$14.57万
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财政年份:2021
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负责人:Decaluwe Hlène
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依托单位:
Gamma(c)-dependent cytokines in CD8 T cell differentiation and exhaustion
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批准号:281894
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项目类别:Operating Grants
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资助金额:$48.29万
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财政年份:2013
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负责人:Decaluwe Hlène
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依托单位:
国内基金
海外基金
中国北方人群肺癌患者Cancer/Testis抗原表达谱绘制表位鉴定及功能性抗原特异性CTL制备研究
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批准号:81673007
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项目类别:面上项目
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资助金额:54.0万元
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批准年份:2016
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负责人:金时
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依托单位: