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Identification and characterization of microRNAs essential for the development and fitness of chemoresistant AML

Identification and characterization of microRNAs essential for the development and fitness of chemoresistant AML
对化学耐药性 AML 的发展和适应至关重要的 microRNA 的鉴定和表征
批准号:
433601
负责人:
Salmena Leonardo L
金额:
$65.48万
依托单位:
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2020
资助国家:
加拿大
项目状态:
未结题
起止时间:
2020-10-01 至 2025-10-01

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中文摘要
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英文摘要
Drug resistance in patients with acute myeloid leukemia (AML) is a major hurdle for successful therapy. MicroRNA (miRNA) are small RNA with critical roles in most cellular processes that can be disrupted to promote diverse diseases. Aberrant miRNA express
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会议论文
Investigating a novel phosphoinositide-lysosomal signalling axis for pancreatic cancer therapy
  • 批准号:
    477270
  • 项目类别:
    Operating Grants
  • 资助金额:
    $7.29万
  • 财政年份:
    2022
  • 负责人:
    Salmena Leonardo L
  • 依托单位:
Canada Research Chair - Tier 2
  • 批准号:
    415492
  • 项目类别:
  • 资助金额:
    $36.43万
  • 财政年份:
    2019
  • 负责人:
    Salmena Leonardo L
  • 依托单位:
Investigating INPP4B signalling as a target for therapy in leukaemia
  • 批准号:
    380561
  • 项目类别:
    Operating Grants
  • 资助金额:
    $54.34万
  • 财政年份:
    2018
  • 负责人:
    Salmena Leonardo L
  • 依托单位:
Investigating the novel stem cell function of the phosphoinositide phosphatase INPP4B in hematopoiesis and leukemia
  • 批准号:
    351773
  • 项目类别:
    Operating Grants
  • 资助金额:
    $7.29万
  • 财政年份:
    2016
  • 负责人:
    Salmena Leonardo L
  • 依托单位:
海外基金