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Liquid biopsy-based DNA methylation profiling for improved diagnosis and prognostication of primary and metastatic CNS tumors

Liquid biopsy-based DNA methylation profiling for improved diagnosis and prognostication of primary and metastatic CNS tumors
基于液体活检的 DNA 甲基化分析可改善原发性和转移性中枢神经系统肿瘤的诊断和预后
批准号：
435853
负责人：
Zadeh Gelareh
金额：
$83.6万
依托单位：
University Health Network (Toronto)
依托单位国家：
加拿大
项目类别：
Operating Grants
财政年份：
2020
资助国家：
加拿大
项目状态：
未结题
起止时间：
2020-10-01 至 2025-10-01
来源：
https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=435853&lang=en
关键词：
Biomarkers Brain Metastasis Cerebrospinal Fluid Diagnosis Dna Methylation Genomics Glioblastoma Liquid Biopsy Plasma Prognosis

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Currently diagnosing and determining what type of brain tumor a patient has requires surgery, which is associated with significant anxiety and in some cases may cause complications leading to significant morbidity and even mortality. Tumors shed DNA into
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