Green Chemistry

绿色化学

• 批准号: CRC-2017-00201
• 负责人: Harrington, Matthew
• 金额: $ 8.74万
• 依托单位: McGill University
• 依托单位国家: 加拿大
• 项目类别: Canada Research Chairs
• 财政年份: 2020
• 资助国家: 加拿大
• 起止时间: 2020-01-01 至 2021-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=695284
• 关键词: Green; Chemistry

Living organisms rapidly fabricate a range of high performance biopolymeric materials, such as silk, from biomolecular building blocks (e.g. proteins) via bottom-up assembly processes. The goal of the proposed research program is to revolutionize how humans sustainably manufacture materials by elucidating the underlying principles of biological material self-assembly through an innovative and cross-disciplinary approach, with a specific focus on three model systems the mussel byssus, velvet worm slime fibers and mistletoe viscin fibers. Extracted design principles will be translated to the bio-inspired fabrication of novel polymeric materials utilizing advanced manufacturing methods (e.g. microfluidics) with potential biomedical and technological applications.

生物有机体通过自下而上的组装过程从生物分子构建块（例如蛋白质）快速制造一系列高性能生物聚合物材料，例如丝。拟议的研究计划的目标是通过创新和跨学科的方法阐明生物材料自组装的基本原理，彻底改变人类如何可持续地制造材料，特别关注三个模型系统贻贝足丝，天鹅绒蠕虫粘液纤维和槲寄生内脏纤维。提取的设计原则将被转化为利用先进制造方法（例如微流体）的新型聚合物材料的生物启发制造，具有潜在的生物医学和技术应用。