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A trial to evaluate the safety and feasibility of blood-brain brain opening using MRI-guided focused ultrasound in the treatment of Her2-positive breast cancer brain metastases

A trial to evaluate the safety and feasibility of blood-brain brain opening using MRI-guided focused ultrasound in the treatment of Her2-positive breast cancer brain metastases
评估 MRI 引导聚焦超声血脑脑开放治疗 Her2 阳性乳腺癌脑转移的安全性和可行性的试验
批准号：
443060
负责人：
Lipsman Nir
金额：
$7.29万
依托单位：
Sunnybrook Research Institute (Toronto, Ontario)
依托单位国家：
加拿大
项目类别：
Operating Grants
财政年份：
2020
资助国家：
加拿大
项目状态：
已结题
起止时间：
2020-10-01 至 2021-10-01
来源：
https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=443060&lang=en
关键词：
Brain Metastases Breast Cancer Focused Ultrasound Her2 Image-Guided Surgery Indium-111 Trastuzumab

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中文摘要
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英文摘要
Breast cancer is the second most common cancer globally. Approximately 20% of breast cancers are Her2+, and amenable to targeted therapies like trastuzumab, an anti-Her2 receptor antibody. However, trastuzumab has poor penetration past the blood-brain bar
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会议论文
From function to dysfunction: Deep Brain Stimulation and single-unit recording to modulate and probe human neural reward circuitry
  • 批准号：
    230240
  • 项目类别：
    Fellowship Programs
  • 资助金额：
    $12.02万
  • 财政年份：
    2011
  • 负责人：
    Lipsman Nir
  • 依托单位：
    University Health Network (Toronto)
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