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Effects of dexmedetomidine in patients with agitated delirium in palliative care: an open-label phase 1/2 proof-of-concept, feasibility, and dose-finding clinical trial

Effects of dexmedetomidine in patients with agitated delirium in palliative care: an open-label phase 1/2 proof-of-concept, feasibility, and dose-finding clinical trial
右美托咪定对姑息治疗中躁动性谵妄患者的影响：开放标签 1/2 期概念验证、可行性和剂量探索临床试验
批准号：
438488
负责人：
Downar James
金额：
$7.29万
依托单位：
Élisabeth Bruyère Hospital (Ottawa, ON)
依托单位国家：
加拿大
项目类别：
Operating Grants
财政年份：
2020
资助国家：
加拿大
项目状态：
已结题
起止时间：
2020-10-01 至 2021-10-01
来源：
https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=438488&lang=en
关键词：
Agitated Delirium Dexmedetomidine Palliative Care Phase I/Ii Clinical Trial Qualitative Investigation Rousable Sedation

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中文摘要
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英文摘要
Agitated delirium is a common and challenging complication to manage at the end of life. Among imminently dying patients, palliative sedation is often used to manage agitated delirium. However, sedation generally eliminates patients' ability to be alert o
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A mixed-methods study to develop a jurisdiction-level resource allocation framework to guide the use of triage and triage-avoidant strategies during an overwhelming surge in demand for critical and acute care.
  • 批准号：
    460236
  • 项目类别：
    Operating Grants
  • 资助金额：
    $36.42万
  • 财政年份：
    2021
  • 负责人：
    Downar James
  • 依托单位：
    Bruyère Research Institute
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    Operating Grants
  • 资助金额：
    $52.39万
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    Downar James
  • 依托单位：
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Using patient-reported outcomes to improve the quality of palliative care: Establishing priorities and actions for data collection and reporting in Canada
  • 批准号：
    411974
  • 项目类别：
    Miscellaneous Programs
  • 资助金额：
    $1.44万
  • 财政年份：
    2019
  • 负责人：
    Downar James
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国内基金
海外基金
Dexmedetomidine在星形胶质细胞上引起上皮生长因子受体的间接激活
  • 批准号：
    30370451
  • 项目类别：
    面上项目
  • 资助金额：
    21.0万元
  • 批准年份：
    2003
  • 负责人：
    彭亮
  • 依托单位：
    中国医科大学