Oxidation of Parkin is Linked to Neuroprotection in Adult Mammalian Brain
Oxidation of Parkin is Linked to Neuroprotection in Adult Mammalian Brain
批准号:
435202
负责人:
Schlossmacher Michael G
金额:
$64.09万
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2020
资助国家:
加拿大
项目状态:
未结题
起止时间:
2020-10-01 至 2025-10-01
中文摘要
点击翻译按钮获取中文摘要
英文摘要
Goal: We recently discovered an anti-oxidant role for parkin as a redox-active molecule in human brain. Its deficiency leads to young-onset Parkinson disease in humans, but not in animals. Wild-type parkin appears essential to human dopamine-producing cel
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
Investigating Parkinson disease-linked genes in brain health following infections.
-
批准号:346028
-
项目类别:Operating Grants
-
资助金额:$96.91万
-
财政年份:2016
-
负责人:Schlossmacher Michael G
-
依托单位:
MD/PhD Program Grant 2015-2016
-
批准号:335072
-
项目类别:Operating Grants
-
资助金额:$9.62万
-
财政年份:2015
-
负责人:Schlossmacher Michael G
-
依托单位:
MD/PhD Program Grant (starting 2014-15)
-
批准号:315502
-
项目类别:Operating Grants
-
资助金额:$9.62万
-
财政年份:2014
-
负责人:Schlossmacher Michael G
-
依托单位:
MD/PhD Program Grant (starting in 2013-14)
-
批准号:289952
-
项目类别:Operating Grants
-
资助金额:$9.62万
-
财政年份:2013
-
负责人:Schlossmacher Michael G
-
依托单位:
CANADA RESEARCH CHAIRHOLDER / TITULAIRE DE CHAIRE DE RECHERCHE DU CANADA
-
批准号:256410
-
项目类别:
-
资助金额:$36.43万
-
财政年份:2011
-
负责人:Schlossmacher Michael G
-
依托单位:
Cathepsin D Activation: A Target to Reduce Alpha-Synuclein Pathology in a Parkinson's Model
-
批准号:211013
-
项目类别:Operating Grants
-
资助金额:$62.28万
-
财政年份:2010
-
负责人:Schlossmacher Michael G
-
依托单位:
海外基金