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Investigating how TRAF1 Controls Inflammasome Activation in Animal Disease Models of Inflammatory Arthritis and Peritonitis

Investigating how TRAF1 Controls Inflammasome Activation in Animal Disease Models of Inflammatory Arthritis and Peritonitis
研究 TRAF1 如何控制炎症性关节炎和腹膜炎动物疾病模型中的炎症小体激活
批准号:
449429
负责人:
Raspanti Jonathan
金额:
$1.27万
依托单位国家:
加拿大
项目类别:
Studentship Programs
财政年份:
2020
资助国家:
加拿大
项目状态:
已结题
起止时间:
2020-12-01 至 2021-12-01

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英文摘要
IL-1β is a potent cytokine that is released as a part of the innate defense mechanism to invading pathogens. Activation of the NLRP3 inflammasome plays a crucial role in appropriate secretion of IL-1β, and its malfunctioning is a driver of autoi
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