Measuring ventilation in lungs using a novel inert fluorinated (19F) gas multiple breath wash-out MRI technique to quantify treatment response in preschoolers with cystic fibrosis

使用新型惰性氟化 (19F) 气体多次呼吸冲洗 MRI 技术测量肺部通气量，以量化患有囊性纤维化的学龄前儿童的治疗反应

• 批准号: 449322
• 负责人: Alam Faiyza S
• 金额: $ 1.27万
• 依托单位: University of Toronto
• 依托单位国家: 加拿大
• 项目类别: Studentship Programs
• 财政年份: 2020
• 资助国家: 加拿大
• 起止时间: 2020-12-01 至 2021-12-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=449322&lang=en
• 关键词: Cystic Fibrosis; Dynamic; Fluorine; Inert; Lung; Mri; Pediatric; Pfp; Treatment Response; Ventilation

Cystic fibrosis (CF) is an incurable genetic lung disease, so potential therapies must start early to slow disease progression. A treatment called CFTR modulator therapy is promising for CF and works best when started before symptoms are visible in childr

囊性纤维化（CF）是一种无法治愈的遗传性肺部疾病，因此必须尽早开始潜在的治疗方法以减缓疾病进展。一种称为 CFTR 调节剂疗法的治疗方法对治疗 CF 有希望，并且在儿童症状出现之前开始效果最佳。