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Developing a polygenic score to aid in the prediction of cisplatin-induced ototoxicity

Developing a polygenic score to aid in the prediction of cisplatin-induced ototoxicity
开发多基因评分以帮助预测顺铂引起的耳毒性
批准号：
449433
负责人：
Sarvis MacKenzie A
金额：
$1.27万
依托单位：
University of Manitoba
依托单位国家：
加拿大
项目类别：
Studentship Programs
财政年份：
2020
资助国家：
加拿大
项目状态：
已结题
起止时间：
2020-12-01 至 2021-12-01
来源：
https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=449433&lang=en
关键词：
Adverse Drug Reactions Audiology Cisplatin-Induced Ototoxicity Genome-Wide Association Study Hearing Loss Inner Hair Cells Pediatric Oncology Pharmacogenomics Polygenic Scores Precision Medicine

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Cisplatin is a common and effective chemotherapy drug which is used to treat many different types of cancer, and as with many chemotherapeutics, it harms both tumour and healthy cells. One of the most frequent adverse drug reactions seen with cisplatin is
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