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COVID-19 Variant Network - Optimizing polar, small inhibitors of a viral cysteine protease to identify a lead for an oral COVID-19 treatment

COVID-19 Variant Network - Optimizing polar, small inhibitors of a viral cysteine protease to identify a lead for an oral COVID-19 treatment
COVID-19 变体网络 - 优化病毒半胱氨酸蛋白酶的极性小抑制剂，以确定口服 COVID-19 治疗的先导药物
批准号：
443337
负责人：
Lemieux Joanne M
金额：
$7.29万
依托单位：
University of Alberta
依托单位国家：
加拿大
项目类别：
Operating Grants
财政年份：
2021
资助国家：
加拿大
项目状态：
已结题
起止时间：
2021-02-01 至 2022-02-01
来源：
https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=443337&lang=en
关键词：
Antiviral Drugs Co-Crystallization Coronavirus Covid-19 Cysteine Protease Inhibitor Lead Identification Molecular Modelling Sars-Cov-2 Small Molecule Drug Discovery

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英文摘要
The COVID-19 pandemic has caused incredible social, personal and economic upheaval and as of early May 2020 killed 275 000 people world-wide and, tragically, is projected to kill millions more. COVID-19 is caused by the SARS-CoV2 (SARS2) virus, which is a
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COVID-19 Variant Supplement - Optimizing polar, small inhibitors of a viral cysteine protease to identify a lead for an oral COVID-19 treatment
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    443207
  • 项目类别：
    Operating Grants
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    $3.64万
  • 财政年份：
    2021
  • 负责人：
    Lemieux Joanne M
  • 依托单位：
    University of Alberta
Targeting SARS-CoV-2 Main protease and variants for effective antiviral development
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    452190
  • 项目类别：
    Operating Grants
  • 资助金额：
    $62.7万
  • 财政年份：
    2021
  • 负责人：
    Lemieux Joanne M
  • 依托单位：
    University of Alberta
Optimizing polar, small inhibitors of a viral cysteine protease to identify a lead for an oral COVID-19 treatment
  • 批准号：
    429698
  • 项目类别：
    Operating Grants
  • 资助金额：
    $42.63万
  • 财政年份：
    2020
  • 负责人：
    Lemieux Joanne M
  • 依托单位：
    University of Alberta
Synthesis, Structural Studies and Evaluation of Inhibitors of the 3CL Protease of SARS-CoV-2 as Potential Drugs for Treating Infection
  • 批准号：
    422721
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  • 财政年份：
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  • 依托单位：
    University of Alberta
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