Role of the ribosomal protein RACK1 and protein kinases in a -1 programmed ribosomal frameshift of HIV-1

核糖体蛋白 RACK1 和蛋白激酶在 HIV-1 的 -1 程序化核糖体移码中的作用

• 批准号: 194119
• 负责人: Karetnikov Alexey
• 金额: $ 9.83万
• 依托单位: Universit de Montral
• 依托单位国家: 加拿大
• 项目类别: Fellowship Programs
• 财政年份: 2009
• 资助国家: 加拿大
• 起止时间: 2009-10-01 至 2012-10-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=194119&lang=en
• 关键词: Hiv; In Vivo Expression Of Reporter Genes; Molecular Biology; Protein Kinases; Rack1; Retroviruses; Ribosomal E-Site; Ribosomal Frameshift; Sirna-Mediated Knock-Down; Translational Control

Viruses are molecular complexes consisting of a nucleic acid of only one type (DNA or RNA) surrounded by a protein coat. Viruses exist in two forms: resting extracellular form (virion) and actively reproducing (replicating) intracellular form. When virus

病毒是由蛋白质外壳包围的仅一种类型（DNA或RNA）的核酸组成的分子复合物。病毒以两种形式存在：静止的细胞外形式（病毒体）和活跃繁殖（复制）的细胞内形式。当病毒