Cardioprotective effect of a cyclic azapeptide ligand of CD36 against ischemia-reperfusion damage and dysfunction in mice

CD36环状氮杂肽配体对小鼠缺血再灌注损伤和功能障碍的心脏保护作用

• 批准号: 444385
• 负责人: Marleau Sylvie
• 金额: $ 52.94万
• 依托单位: Universit de Montral
• 依托单位国家: 加拿大
• 项目类别: Operating Grants
• 财政年份: 2021
• 资助国家: 加拿大
• 起止时间: 2021-04-01 至 2026-04-01
• 项目状态: 未结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=444385&lang=en
• 关键词: Azapeptides; Cardiomyocyte; Cardioprotection; Cd36 Receptor; Macrophage; Myocardial Ischemia-Reperfusion

Every 7 minutes, an individual dies from a heart attack. In many instances, what happens is that the blood vessels bringing blood and nutrients to the heart are blocked. Blood flow should be restored very rapidly for the heart cells to survive and limit t

每7分钟就有一个人死于心脏病发作。在许多情况下，发生的情况是将血液和营养物质输送到心脏的血管被阻塞。血液流动应该非常迅速地恢复，以使心脏细胞存活并限制心脏的收缩。